業績
論文2008年
- Song, M.S., Song, S.J., Kim, S.J., Nakayama, K., Nakayama, K.I. & Lim, D.S.;Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G1-S transition. Oncogene 27, 3176-3185 (2008).
- Qi, J., Nakayama, K., Gaitonde, S., Goydos, J.S., Krajewski, S., Eroshkin, A., Bar-Sagi, D., Bowtell, D. & Ronai, Z.;The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways. Proc. Natl. Acad. Sci. USA 105, 16713-16718 (2008).
- Ohsaki, K., Oishi, K., Kozono, Y., Nakayama, K., Nakayama, K.I. & Ishida, N.;The Role of {beta}-TrCP1 and {beta}-TrCP2 in Circadian Rhythm Generation by Mediating Degradation of Clock Protein PER2. J. Biochem. 144, 609-618 (2008).
- Miranda-Carboni, G.A., Krum, S.A., Yee, K., Nava, M., Deng, Q.E., Pervin, S., Collado-Hidalgo, A., Galic, Z., Zack, J.A., Nakayama, K., Nakayama, K.I. & Lane, T.F.;A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. Genes Dev. 22, 3121-3134 (2008).
- Matsuoka, S., Oike, Y., Onoyama, I., Iwama, A., Arai, F., Takubo, K., Mashimo, Y., Oguro, H., Nitta, E., Ito, K., Miyamoto, K., Yoshiwara, H., Hosokawa, K., Nakamura, Y., Gomei, Y., Iwasaki, H., Hayashi, Y., Matsuzaki, Y., Nakayama, K., Ikeda, Y., Hata, A., Chiba, S., Nakayama, K.I. & Suda, T.;Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL. Genes Dev. 22, 986-991 (2008).
- Ishikawa, Y., Onoyama, I., Nakayama, K.I. & Nakayama, K.;Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7. Oncogene 27, 6164-6174 (2008).
- Gallegos, J.R., Litersky, J., Lee, H., Sun, Y., Nakayama, K. & Lu, H.;SCFbeta TrCP1 activates and ubiquitylates TAp63gamma. J. Biol. Chem. 283, 66-75 (2008).
- Chen, Q., Xie, W., Kuhn, D.J., Voorhees, P.M., Lopez-Girona, A., Mendy, D., Corral, L.G., Krenitsky, V.P., Xu, W., Moutouh-de Parseval, L., Webb, D.R., Mercurio, F., Nakayama, K.I., Nakayama, K. & Orlowski, R.Z.;Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy. Blood 111, 4690-4699 (2008).